Hexarelin vs TB-500

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Hexarelin

Hexarelin is a potent synthetic hexapeptide growth hormone secretagogue. It provides the strongest GH release among GHRPs but is associated with rapid desensitization of receptors.

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TB-500

Thymosin Beta-4 (TB-500) is a naturally occurring peptide present in almost all human and animal cells. It plays a crucial role in tissue repair and regeneration.

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Side-by-Side Comparison

Aspect	Hexarelin	TB-500
Dose Range	100 mcg–300 mcg	2 mg–2.5 mg
Frequency	2x daily	Less than daily
Cycle Length	8–12 weeks	4–8 weeks
Route	subcutaneous	subcutaneous
Mechanism	Acts as a ghrelin mimetic with high potency at the GHS receptor. Provides powerful GH release but receptor desensitization occurs faster than with other GHRPs, requiring cycling.	TB-500 promotes cell migration and differentiation, regulates actin (a cell-building protein), and reduces inflammation. It supports the formation of new blood vessels and wound healing.
Typical Dosage	Typical dosing: 100-200mcg administered 2-3 times daily for 4-6 weeks, followed by an equal off period to allow receptor resensitization.	Research protocols typically use 2-2.5mg twice weekly during the loading phase, followed by maintenance dosing of 2mg every 2 weeks.
Administration	Subcutaneous injection. Cycling is essential to maintain effectiveness. Often used in short bursts rather than continuous protocols.	Administered via subcutaneous or intramuscular injection. Some protocols suggest injection near injury sites.
Side Effects	Water retention, cortisol and prolactin increase, hunger (moderate), tingling, and potential blood pressure effects.	May cause temporary fatigue, headache, or localized irritation at injection sites.
Best For	Muscle Growth Recovery & Healing	Muscle Growth Recovery & Healing