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Hexarelin vs Selank

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Hexarelin

Hexarelin is a potent synthetic hexapeptide growth hormone secretagogue. It provides the strongest GH release among GHRPs but is associated with rapid desensitization of receptors.

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Selank

Selank is a synthetic peptide derived from the naturally occurring immunomodulatory peptide tuftsin. Developed in Russia for anxiety and cognitive enhancement.

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Side-by-Side Comparison

AspectHexarelinSelank
MechanismActs as a ghrelin mimetic with high potency at the GHS receptor. Provides powerful GH release but receptor desensitization occurs faster than with other GHRPs, requiring cycling.Modulates the expression of brain-derived neurotrophic factor (BDNF) and affects serotonin and norepinephrine systems. Has immunomodulatory and anxiolytic properties.
Typical DosageTypical dosing: 100-200mcg administered 2-3 times daily for 4-6 weeks, followed by an equal off period to allow receptor resensitization.Intranasal administration: 250-500mcg 2-3 times daily. Subcutaneous: 250-500mcg daily.
AdministrationSubcutaneous injection. Cycling is essential to maintain effectiveness. Often used in short bursts rather than continuous protocols.Most commonly administered intranasally for cognitive effects. Can also be injected subcutaneously.
Side EffectsWater retention, cortisol and prolactin increase, hunger (moderate), tingling, and potential blood pressure effects.Generally well-tolerated. Some users report mild fatigue or nasal irritation with intranasal use.
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Key Differences

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