GHRP-6 vs AHK-Cu

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

GHRP-6

Growth Hormone Releasing Peptide 6 (GHRP-6) is one of the first synthetic growth hormone secretagogues discovered. It stimulates significant GH release but is known for causing intense hunger.

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AHK-Cu

AHK-Cu (Copper Tripeptide-3, Alanine-Histidine-Lysine Copper) is a copper peptide similar to GHK-Cu but with different properties. It's used for hair growth and skin rejuvenation applications.

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Side-by-Side Comparison

AspectGHRP-6AHK-Cu
MechanismActs as a ghrelin mimetic, binding to the GHS-R receptor in the pituitary and hypothalamus. Stimulates GH release and also significantly increases appetite by mimicking ghrelin's hunger-signaling effects.The copper-binding tripeptide stimulates collagen synthesis and may promote hair follicle enlargement. Works similarly to GHK-Cu but may have distinct receptor interactions.
Typical DosageTypical dosing: 100-300mcg administered 2-3 times daily. Often combined with GHRH peptides like CJC-1295 for synergistic effects.Topical: 0.5-2% concentration in serums for skin or scalp applications. Often combined with other growth factors for hair formulations.
AdministrationSubcutaneous injection. Best administered on an empty stomach. The strong hunger response can be beneficial for those trying to gain weight but challenging for cutting.Topical application to skin or scalp. Can be used with microneedling for enhanced penetration. May cause temporary blue-green tint at high concentrations.
Side EffectsIntense hunger (most notable effect), water retention, increased cortisol and prolactin, tingling/numbness, and potential blood pressure changes.Generally well-tolerated. May cause skin irritation in sensitive individuals. Temporary discoloration possible.
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Key Differences

Unique to GHRP-6:

Unique to AHK-Cu:

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