GHRP-2 vs Syn-Ake

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

GHRP-2

Growth Hormone Releasing Peptide 2 (GHRP-2) is considered one of the most potent GHRPs available. It provides strong GH release with moderate hunger increase compared to GHRP-6.

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Syn-Ake

Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) is a synthetic tripeptide that mimics the effect of Waglerin-1, a peptide found in Temple Viper venom. It's used in cosmetics for anti-wrinkle effects.

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Side-by-Side Comparison

AspectGHRP-2Syn-Ake
MechanismBinds to the ghrelin receptor (GHS-R) to stimulate GH release from the pituitary. Also has some direct effects on the hypothalamus. Causes less appetite increase than GHRP-6.Acts as a competitive antagonist at the nicotinic acetylcholine receptor, reducing muscle contractions similar to Botox but through a different mechanism. Provides muscle-relaxing effects when applied topically.
Typical DosageTypical dosing: 100-300mcg administered 2-3 times daily. Often stacked with GHRH peptides for enhanced GH release.Topical: 1-4% concentration in serums or creams. Applied 1-2 times daily to target areas like forehead and crow's feet.
AdministrationSubcutaneous injection on an empty stomach. Can be used at bedtime to enhance natural GH pulse during sleep.Topical application only. Should be applied to clean skin. Often combined with other anti-aging peptides for synergistic effects.
Side EffectsModerate hunger increase, water retention, potential prolactin and cortisol elevation (less than GHRP-6), tingling sensations.Generally well-tolerated topically. Rare reports of mild skin irritation or sensitivity.
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Key Differences

Unique to GHRP-2:

Unique to Syn-Ake:

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