GHRP-2 vs IGF-1 LR3

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

GHRP-2

Growth Hormone Releasing Peptide 2 (GHRP-2) is considered one of the most potent GHRPs available. It provides strong GH release with moderate hunger increase compared to GHRP-6.

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IGF-1 LR3

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified version of IGF-1 with extended half-life and enhanced potency. The modifications prevent binding to IGF binding proteins, increasing bioavailability.

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Side-by-Side Comparison

Aspect	GHRP-2	IGF-1 LR3
Dose Range	100 mcg–300 mcg	20 mcg–100 mcg
Frequency	3x daily	1x daily
Cycle Length	8–12 weeks	4–6 weeks
Route	subcutaneous	subcutaneous
Mechanism	Binds to the ghrelin receptor (GHS-R) to stimulate GH release from the pituitary. Also has some direct effects on the hypothalamus. Causes less appetite increase than GHRP-6.	Binds to IGF-1 receptors to promote protein synthesis, muscle growth, and fat metabolism. The LR3 modification (13 amino acid extension and arginine substitution) extends half-life from minutes to 20-30 hours.
Typical Dosage	Typical dosing: 100-300mcg administered 2-3 times daily. Often stacked with GHRH peptides for enhanced GH release.	Research protocols typically use 20-100mcg daily, often divided into multiple injections or administered bilaterally to target muscles.
Administration	Subcutaneous injection on an empty stomach. Can be used at bedtime to enhance natural GH pulse during sleep.	Intramuscular injection (site-specific growth) or subcutaneous for systemic effects. Often cycled 4-6 weeks on, equal time off.
Side Effects	Moderate hunger increase, water retention, potential prolactin and cortisol elevation (less than GHRP-6), tingling sensations.	Hypoglycemia, joint pain, water retention, potential jaw/hand growth with extended use, and injection site reactions.
Best For	Muscle Growth Fat Loss Sleep Quality	Muscle Growth Fat Loss Recovery & Healing