GHRP-2 vs Dihexa

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

GHRP-2

Growth Hormone Releasing Peptide 2 (GHRP-2) is considered one of the most potent GHRPs available. It provides strong GH release with moderate hunger increase compared to GHRP-6.

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Dihexa

Dihexa is a nootropic peptide derived from angiotensin IV. It has shown remarkable cognitive-enhancing properties in animal studies, being described as potentially millions of times more potent than BDNF.

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Side-by-Side Comparison

AspectGHRP-2Dihexa
MechanismBinds to the ghrelin receptor (GHS-R) to stimulate GH release from the pituitary. Also has some direct effects on the hypothalamus. Causes less appetite increase than GHRP-6.Acts as a hepatocyte growth factor (HGF) potentiator by binding to its receptor c-Met. Promotes synaptogenesis, neuronal survival, and cognitive enhancement through this pathway.
Typical DosageTypical dosing: 100-300mcg administered 2-3 times daily. Often stacked with GHRH peptides for enhanced GH release.Research dosing is highly variable due to extreme potency. Typical range: 10-40mg orally or sublingually. Start with lowest doses due to potency.
AdministrationSubcutaneous injection on an empty stomach. Can be used at bedtime to enhance natural GH pulse during sleep.Can be taken orally, sublingually, or intranasally. Extremely potent - careful dosing is essential. Best used cyclically.
Side EffectsModerate hunger increase, water retention, potential prolactin and cortisol elevation (less than GHRP-6), tingling sensations.Limited human data. Reported effects include headache, temporary brain fog during adjustment, and potential mood changes.
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Key Differences

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