Exenatide vs Thymulin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Exenatide

Exenatide was the first GLP-1 receptor agonist approved in the US, derived from a compound found in Gila monster saliva. Available as Byetta (twice daily) and Bydureon (once weekly extended-release).

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Thymulin

Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation.

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Side-by-Side Comparison

AspectExenatideThymulin
MechanismSynthetic version of exendin-4, which activates GLP-1 receptors to enhance glucose-dependent insulin secretion, suppress glucagon, slow gastric emptying, and promote satiety.Requires zinc for biological activity. Promotes T-cell differentiation, modulates cytokine production, and influences neuroendocrine function. Levels decline significantly with age.
Typical DosageByetta: 5mcg twice daily for 1 month, then 10mcg twice daily. Bydureon: 2mg subcutaneously once weekly.Research protocols vary. Often studied alongside zinc supplementation. Typical research doses in the microgram range.
AdministrationByetta: Inject within 60 minutes before morning and evening meals. Bydureon: Any time of day, with or without meals. Do not mix with insulin in same syringe.Subcutaneous or intramuscular injection in research settings. Requires adequate zinc status for activity.
Side EffectsNausea (especially initially), vomiting, diarrhea, dizziness, headache, and injection site reactions (particularly with Bydureon).Limited data on exogenous administration. Theoretical effects on immune function require monitoring.
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Key Differences

Unique to Exenatide:

Unique to Thymulin:

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