Dulaglutide vs Thymulin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Dulaglutide

Dulaglutide (Trulicity) is a once-weekly GLP-1 receptor agonist for type 2 diabetes. Its larger molecular size from fusion with an Fc fragment extends half-life and may reduce some GI side effects.

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Thymulin

Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation.

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Side-by-Side Comparison

AspectDulaglutideThymulin
MechanismGLP-1 analog fused to a modified human IgG4 Fc fragment, providing extended duration of action. Activates GLP-1 receptors for glucose-dependent insulin secretion and appetite suppression.Requires zinc for biological activity. Promotes T-cell differentiation, modulates cytokine production, and influences neuroendocrine function. Levels decline significantly with age.
Typical DosageStart at 0.75mg once weekly, may increase to 1.5mg, 3mg, or maximum 4.5mg weekly based on glycemic response.Research protocols vary. Often studied alongside zinc supplementation. Typical research doses in the microgram range.
AdministrationSubcutaneous injection once weekly, any time of day, with or without food. Comes in pre-filled single-dose pens.Subcutaneous or intramuscular injection in research settings. Requires adequate zinc status for activity.
Side EffectsNausea, diarrhea, vomiting, abdominal pain, decreased appetite. Generally well-tolerated with gradual dose titration.Limited data on exogenous administration. Theoretical effects on immune function require monitoring.
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Key Differences

Unique to Dulaglutide:

Unique to Thymulin:

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