DSIP vs Dihexa

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

DSIP

Delta Sleep-Inducing Peptide is a neuropeptide that promotes delta wave sleep, the deepest and most restorative phase of the sleep cycle.

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Dihexa

Dihexa is a nootropic peptide derived from angiotensin IV. It has shown remarkable cognitive-enhancing properties in animal studies, being described as potentially millions of times more potent than BDNF.

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Side-by-Side Comparison

AspectDSIPDihexa
MechanismModulates sleep-wake cycles by affecting sleep spindles and delta rhythms. May also influence stress hormones and have analgesic properties.Acts as a hepatocyte growth factor (HGF) potentiator by binding to its receptor c-Met. Promotes synaptogenesis, neuronal survival, and cognitive enhancement through this pathway.
Typical DosageTypical dosing: 100-300mcg administered 30 minutes before sleep. Some protocols use it cyclically.Research dosing is highly variable due to extreme potency. Typical range: 10-40mg orally or sublingually. Start with lowest doses due to potency.
AdministrationSubcutaneous or intramuscular injection before bedtime. Some users report better results with cyclical use.Can be taken orally, sublingually, or intranasally. Extremely potent - careful dosing is essential. Best used cyclically.
Side EffectsMay cause grogginess upon waking, vivid dreams, or temporary headaches.Limited human data. Reported effects include headache, temporary brain fog during adjustment, and potential mood changes.
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Key Differences

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