Dihexa vs Epigen

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Dihexa

Dihexa is a nootropic peptide derived from angiotensin IV. It has shown remarkable cognitive-enhancing properties in animal studies, being described as potentially millions of times more potent than BDNF.

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Epigen

Epigen is a member of the epidermal growth factor (EGF) family. It plays roles in skin regeneration and has been studied for wound healing and anti-aging applications.

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Side-by-Side Comparison

AspectDihexaEpigen
MechanismActs as a hepatocyte growth factor (HGF) potentiator by binding to its receptor c-Met. Promotes synaptogenesis, neuronal survival, and cognitive enhancement through this pathway.Binds to and activates the EGF receptor (EGFR), promoting cell proliferation, migration, and differentiation. Involved in skin homeostasis and repair processes.
Typical DosageResearch dosing is highly variable due to extreme potency. Typical range: 10-40mg orally or sublingually. Start with lowest doses due to potency.Topical: Typically used at low concentrations (ppm to low %) in cosmetic formulations. Research applications vary.
AdministrationCan be taken orally, sublingually, or intranasally. Extremely potent - careful dosing is essential. Best used cyclically.Primarily topical application for skincare. Research may use other routes for systemic effects.
Side EffectsLimited human data. Reported effects include headache, temporary brain fog during adjustment, and potential mood changes.Topical use generally well-tolerated. Theoretical concerns about promoting cell proliferation.
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Key Differences

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