Cerebrolysin vs Leuphasyl

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Cerebrolysin

Cerebrolysin is a mixture of low-molecular-weight neuropeptides and free amino acids derived from purified pig brain proteins. It is approved in many countries for stroke, traumatic brain injury, and dementia.

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Leuphasyl

Leuphasyl (Pentapeptide-18) is a cosmetic peptide that reduces muscle tension through a mechanism similar to enkephalins. Often combined with Syn-Ake for enhanced anti-wrinkle effects.

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Side-by-Side Comparison

AspectCerebrolysinLeuphasyl
MechanismContains multiple neurotrophic factors that promote neuroplasticity, reduce neuronal apoptosis, and support synaptic function. Has both neurotrophic and neuroprotective properties.Mimics enkephalin and binds to enkephalin receptors on muscle cells, reducing acetylcholine release and thereby decreasing muscle contraction intensity.
Typical DosageClinical dosing: 10-30ml IV daily for acute conditions. Research use: 5-10ml IM daily for cognitive enhancement. Treatment courses typically last 10-20 days.Topical: 3-8% concentration in serums. Often used in combination products with other muscle-relaxing peptides.
AdministrationAdministered via intramuscular or intravenous injection. IV administration is typically used in clinical settings. IM can be used for research purposes.Topical application to expression lines. Best results with consistent twice-daily use over 8+ weeks.
Side EffectsGenerally well-tolerated. May cause dizziness, headache, sweating, or injection site reactions. Rare cases of agitation or confusion.Very well-tolerated topically. No significant adverse effects reported at cosmetic concentrations.
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Key Differences

Unique to Cerebrolysin:

Unique to Leuphasyl:

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