AHK-Cu vs SHLP2

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

AHK-Cu

AHK-Cu (Copper Tripeptide-3, Alanine-Histidine-Lysine Copper) is a copper peptide similar to GHK-Cu but with different properties. It's used for hair growth and skin rejuvenation applications.

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SHLP2

SHLP2 (Small Humanin-Like Peptide 2) is a mitochondrial-derived peptide similar to humanin. It has shown insulin-sensitizing and cytoprotective effects in research, with potential metabolic benefits.

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Side-by-Side Comparison

AspectAHK-CuSHLP2
MechanismThe copper-binding tripeptide stimulates collagen synthesis and may promote hair follicle enlargement. Works similarly to GHK-Cu but may have distinct receptor interactions.Enhances insulin sensitivity and glucose uptake. Provides cytoprotective effects similar to humanin. May act through similar but distinct receptor pathways.
Typical DosageTopical: 0.5-2% concentration in serums for skin or scalp applications. Often combined with other growth factors for hair formulations.Research compound with doses in the microgram to low milligram range studied in animal models. Human dosing not established.
AdministrationTopical application to skin or scalp. Can be used with microneedling for enhanced penetration. May cause temporary blue-green tint at high concentrations.Subcutaneous or intraperitoneal injection in research settings. Various SHLP analogs (1-6) have different properties.
Side EffectsGenerally well-tolerated. May cause skin irritation in sensitive individuals. Temporary discoloration possible.Limited data. Animal studies suggest good tolerability. May affect glucose metabolism.
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Key Differences

Unique to AHK-Cu:

Unique to SHLP2:

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