AHK-Cu vs BNP (B-type Natriuretic Peptide)

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

AHK-Cu

AHK-Cu (Copper Tripeptide-3, Alanine-Histidine-Lysine Copper) is a copper peptide similar to GHK-Cu but with different properties. It's used for hair growth and skin rejuvenation applications.

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BNP (B-type Natriuretic Peptide)

BNP is a cardiac neurohormone released primarily by ventricles in response to volume/pressure overload. It's a major biomarker for heart failure and has therapeutic applications as nesiritide.

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Side-by-Side Comparison

AspectAHK-CuBNP (B-type Natriuretic Peptide)
MechanismThe copper-binding tripeptide stimulates collagen synthesis and may promote hair follicle enlargement. Works similarly to GHK-Cu but may have distinct receptor interactions.Similar to ANP - activates NPR-A receptors to produce vasodilation, natriuresis, and RAAS suppression. Released in response to ventricular wall stress.
Typical DosageTopical: 0.5-2% concentration in serums for skin or scalp applications. Often combined with other growth factors for hair formulations.Nesiritide (recombinant BNP): 2mcg/kg IV bolus followed by 0.01mcg/kg/min continuous infusion for acute decompensated heart failure.
AdministrationTopical application to skin or scalp. Can be used with microneedling for enhanced penetration. May cause temporary blue-green tint at high concentrations.Intravenous administration only. Used in acute care settings for heart failure. BNP levels also used diagnostically.
Side EffectsGenerally well-tolerated. May cause skin irritation in sensitive individuals. Temporary discoloration possible.Hypotension (common and dose-limiting), headache, nausea, and potential renal function worsening in some patients.
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Key Differences

Unique to AHK-Cu:

Unique to BNP (B-type Natriuretic Peptide):

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