Adamax vs Leuphasyl

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Adamax

Adamax is a modified version of Semax with an adamantane group attached, designed to enhance its nootropic effects and extend duration of action compared to standard Semax.

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Leuphasyl

Leuphasyl (Pentapeptide-18) is a cosmetic peptide that reduces muscle tension through a mechanism similar to enkephalins. Often combined with Syn-Ake for enhanced anti-wrinkle effects.

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Side-by-Side Comparison

AspectAdamaxLeuphasyl
MechanismSimilar to Semax - enhances BDNF expression and modulates dopamine/serotonin systems. The adamantane modification may increase lipophilicity and CNS penetration.Mimics enkephalin and binds to enkephalin receptors on muscle cells, reducing acetylcholine release and thereby decreasing muscle contraction intensity.
Typical DosageIntranasal: 100-500mcg 1-2 times daily. Lower doses than standard Semax may be effective due to enhanced potency.Topical: 3-8% concentration in serums. Often used in combination products with other muscle-relaxing peptides.
AdministrationIntranasal spray is most common route. More stable than standard Semax. Often used for acute cognitive enhancement.Topical application to expression lines. Best results with consistent twice-daily use over 8+ weeks.
Side EffectsSimilar to Semax - possible irritability, hair shedding, or overstimulation. May have stronger effects than standard Semax.Very well-tolerated topically. No significant adverse effects reported at cosmetic concentrations.
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Key Differences

Unique to Adamax:

Unique to Leuphasyl:

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