Setmelanotide Dosage Guide
Complete guide to Setmelanotide dosing protocols, administration methods, and safety considerations for research purposes.
NOT Medical Advice
The dosage and calculator information provided is for educational and research purposes only. Peptides are not approved by the FDA for human use. Individual responses vary significantly. Always consult with a qualified healthcare professional before making any decisions related to peptide research or use.
Dosage Overview
Dose Range
1 mg - 3 mg
Route
subcutaneous
Frequency
1x daily
Cycle Length
12-52 weeks
Reconstitution
Vial Size
5 mg
BAC Water
2.0 ml
Concentration
2,500 mcg/ml
Detailed Dosage Information
Adults: Start 2mg daily, titrate based on tolerability up to 3mg daily. Pediatrics (6+): Weight-based dosing starting at 1mg daily.
Administration Method
Subcutaneous injection once daily. Requires genetic testing to confirm eligible mutations before prescribing.
Research Use Only: All dosage ranges and calculations are derived from published research literature and are provided for educational purposes. These are not prescriptions or medical recommendations. Consult a healthcare professional before any use.
Quick Calculator
Concentration: 2,500 mcg/ml
Volume to inject: 0.40 ml
Syringe units (U-100): 40.0 units
Pre-filled with Setmelanotide defaults. Adjust values as needed.
Side Effects to Monitor
Injection site reactions, skin hyperpigmentation, spontaneous penile erections, depression, and suicidal ideation (boxed warning). GI effects less common than GLP-1s.
Safety Considerations & Risks
Boxed warning for depression and suicidal ideation - requires monitoring. May cause sexual adverse reactions. Only for genetically confirmed obesity.