Setmelanotide Dosage Guide

Complete guide to Setmelanotide dosing protocols, administration methods, and safety considerations for research purposes.

Research Use Only: The dosage information provided is for educational and research purposes. Peptides are not approved by the FDA for human use. Always consult with a healthcare professional.

Recommended Dosage

Adults: Start 2mg daily, titrate based on tolerability up to 3mg daily. Pediatrics (6+): Weight-based dosing starting at 1mg daily.

Administration Method

Subcutaneous injection once daily. Requires genetic testing to confirm eligible mutations before prescribing.

Side Effects to Monitor

Injection site reactions, skin hyperpigmentation, spontaneous penile erections, depression, and suicidal ideation (boxed warning). GI effects less common than GLP-1s.

Safety Considerations & Risks

Boxed warning for depression and suicidal ideation - requires monitoring. May cause sexual adverse reactions. Only for genetically confirmed obesity.