Pramlintide Dosage Guide
Complete guide to Pramlintide dosing protocols, administration methods, and safety considerations for research purposes.
Research Use Only: The dosage information provided is for educational and research purposes. Peptides are not approved by the FDA for human use. Always consult with a healthcare professional.
Recommended Dosage
Type 1: Start 15mcg before meals, titrate to 30-60mcg. Type 2: Start 60mcg, may increase to 120mcg. Always with meal containing 30+ grams carbs or 250+ calories.
Administration Method
Subcutaneous injection immediately before major meals. Must reduce mealtime insulin by 50% when starting to prevent hypoglycemia. Never mix with insulin.
Side Effects to Monitor
Nausea (very common initially), headache, anorexia, vomiting, and abdominal pain. GI effects typically improve over time.
Safety Considerations & Risks
Severe hypoglycemia risk, especially in type 1 diabetes. Boxed warning about insulin-induced severe hypoglycemia. Requires careful dose management.