TB-500 vs Syn-Ake

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

TB-500

Thymosin Beta-4 (TB-500) is a naturally occurring peptide present in almost all human and animal cells. It plays a crucial role in tissue repair and regeneration.

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Syn-Ake

Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) is a synthetic tripeptide that mimics the effect of Waglerin-1, a peptide found in Temple Viper venom. It's used in cosmetics for anti-wrinkle effects.

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Side-by-Side Comparison

AspectTB-500Syn-Ake
MechanismTB-500 promotes cell migration and differentiation, regulates actin (a cell-building protein), and reduces inflammation. It supports the formation of new blood vessels and wound healing.Acts as a competitive antagonist at the nicotinic acetylcholine receptor, reducing muscle contractions similar to Botox but through a different mechanism. Provides muscle-relaxing effects when applied topically.
Typical DosageResearch protocols typically use 2-2.5mg twice weekly during the loading phase, followed by maintenance dosing of 2mg every 2 weeks.Topical: 1-4% concentration in serums or creams. Applied 1-2 times daily to target areas like forehead and crow's feet.
AdministrationAdministered via subcutaneous or intramuscular injection. Some protocols suggest injection near injury sites.Topical application only. Should be applied to clean skin. Often combined with other anti-aging peptides for synergistic effects.
Side EffectsMay cause temporary fatigue, headache, or localized irritation at injection sites.Generally well-tolerated topically. Rare reports of mild skin irritation or sensitivity.
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Key Differences

Unique to TB-500:

Unique to Syn-Ake:

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