TB-500 vs Palmitoyl Tetrapeptide-7

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

TB-500

Thymosin Beta-4 (TB-500) is a naturally occurring peptide present in almost all human and animal cells. It plays a crucial role in tissue repair and regeneration.

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Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 is an anti-inflammatory peptide that reduces IL-6 secretion. Combined with Palmitoyl Tripeptide-1, it forms Matrixyl 3000, addressing both collagen production and inflammation.

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Side-by-Side Comparison

AspectTB-500Palmitoyl Tetrapeptide-7
MechanismTB-500 promotes cell migration and differentiation, regulates actin (a cell-building protein), and reduces inflammation. It supports the formation of new blood vessels and wound healing.Suppresses interleukin-6 (IL-6) production, reducing inflammation that contributes to skin aging. The anti-inflammatory effect complements collagen-stimulating peptides.
Typical DosageResearch protocols typically use 2-2.5mg twice weekly during the loading phase, followed by maintenance dosing of 2mg every 2 weeks.Topical: Usually combined with Palmitoyl Tripeptide-1 at similar concentrations (2-4%) in the Matrixyl 3000 complex.
AdministrationAdministered via subcutaneous or intramuscular injection. Some protocols suggest injection near injury sites.Topical application with other anti-aging actives. The palmitoyl group enhances delivery into the skin.
Side EffectsMay cause temporary fatigue, headache, or localized irritation at injection sites.Excellent tolerability profile. Anti-inflammatory properties may actually soothe sensitive skin.
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Key Differences

Unique to TB-500:

Unique to Palmitoyl Tetrapeptide-7:

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