TB-500 vs NA-Semax Amidate

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

TB-500

Thymosin Beta-4 (TB-500) is a naturally occurring peptide present in almost all human and animal cells. It plays a crucial role in tissue repair and regeneration.

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NA-Semax Amidate

NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.

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Side-by-Side Comparison

AspectTB-500NA-Semax Amidate
MechanismTB-500 promotes cell migration and differentiation, regulates actin (a cell-building protein), and reduces inflammation. It supports the formation of new blood vessels and wound healing.Maintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action.
Typical DosageResearch protocols typically use 2-2.5mg twice weekly during the loading phase, followed by maintenance dosing of 2mg every 2 weeks.Intranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax.
AdministrationAdministered via subcutaneous or intramuscular injection. Some protocols suggest injection near injury sites.Intranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution.
Side EffectsMay cause temporary fatigue, headache, or localized irritation at injection sites.May cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated.
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Key Differences

Unique to TB-500:

Unique to NA-Semax Amidate:

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