Syn-Ake vs AHK-Cu

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Syn-Ake

Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) is a synthetic tripeptide that mimics the effect of Waglerin-1, a peptide found in Temple Viper venom. It's used in cosmetics for anti-wrinkle effects.

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AHK-Cu

AHK-Cu (Copper Tripeptide-3, Alanine-Histidine-Lysine Copper) is a copper peptide similar to GHK-Cu but with different properties. It's used for hair growth and skin rejuvenation applications.

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Side-by-Side Comparison

AspectSyn-AkeAHK-Cu
MechanismActs as a competitive antagonist at the nicotinic acetylcholine receptor, reducing muscle contractions similar to Botox but through a different mechanism. Provides muscle-relaxing effects when applied topically.The copper-binding tripeptide stimulates collagen synthesis and may promote hair follicle enlargement. Works similarly to GHK-Cu but may have distinct receptor interactions.
Typical DosageTopical: 1-4% concentration in serums or creams. Applied 1-2 times daily to target areas like forehead and crow's feet.Topical: 0.5-2% concentration in serums for skin or scalp applications. Often combined with other growth factors for hair formulations.
AdministrationTopical application only. Should be applied to clean skin. Often combined with other anti-aging peptides for synergistic effects.Topical application to skin or scalp. Can be used with microneedling for enhanced penetration. May cause temporary blue-green tint at high concentrations.
Side EffectsGenerally well-tolerated topically. Rare reports of mild skin irritation or sensitivity.Generally well-tolerated. May cause skin irritation in sensitive individuals. Temporary discoloration possible.
Best For

What They Have in Common

Both Syn-Ake and AHK-Cu are commonly used for:

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