SHLP2 vs Epigen

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

SHLP2

SHLP2 (Small Humanin-Like Peptide 2) is a mitochondrial-derived peptide similar to humanin. It has shown insulin-sensitizing and cytoprotective effects in research, with potential metabolic benefits.

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Epigen

Epigen is a member of the epidermal growth factor (EGF) family. It plays roles in skin regeneration and has been studied for wound healing and anti-aging applications.

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Side-by-Side Comparison

AspectSHLP2Epigen
MechanismEnhances insulin sensitivity and glucose uptake. Provides cytoprotective effects similar to humanin. May act through similar but distinct receptor pathways.Binds to and activates the EGF receptor (EGFR), promoting cell proliferation, migration, and differentiation. Involved in skin homeostasis and repair processes.
Typical DosageResearch compound with doses in the microgram to low milligram range studied in animal models. Human dosing not established.Topical: Typically used at low concentrations (ppm to low %) in cosmetic formulations. Research applications vary.
AdministrationSubcutaneous or intraperitoneal injection in research settings. Various SHLP analogs (1-6) have different properties.Primarily topical application for skincare. Research may use other routes for systemic effects.
Side EffectsLimited data. Animal studies suggest good tolerability. May affect glucose metabolism.Topical use generally well-tolerated. Theoretical concerns about promoting cell proliferation.
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Key Differences

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