Palmitoyl Tetrapeptide-7 vs AHK-Cu

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 is an anti-inflammatory peptide that reduces IL-6 secretion. Combined with Palmitoyl Tripeptide-1, it forms Matrixyl 3000, addressing both collagen production and inflammation.

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AHK-Cu

AHK-Cu (Copper Tripeptide-3, Alanine-Histidine-Lysine Copper) is a copper peptide similar to GHK-Cu but with different properties. It's used for hair growth and skin rejuvenation applications.

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Side-by-Side Comparison

AspectPalmitoyl Tetrapeptide-7AHK-Cu
MechanismSuppresses interleukin-6 (IL-6) production, reducing inflammation that contributes to skin aging. The anti-inflammatory effect complements collagen-stimulating peptides.The copper-binding tripeptide stimulates collagen synthesis and may promote hair follicle enlargement. Works similarly to GHK-Cu but may have distinct receptor interactions.
Typical DosageTopical: Usually combined with Palmitoyl Tripeptide-1 at similar concentrations (2-4%) in the Matrixyl 3000 complex.Topical: 0.5-2% concentration in serums for skin or scalp applications. Often combined with other growth factors for hair formulations.
AdministrationTopical application with other anti-aging actives. The palmitoyl group enhances delivery into the skin.Topical application to skin or scalp. Can be used with microneedling for enhanced penetration. May cause temporary blue-green tint at high concentrations.
Side EffectsExcellent tolerability profile. Anti-inflammatory properties may actually soothe sensitive skin.Generally well-tolerated. May cause skin irritation in sensitive individuals. Temporary discoloration possible.
Best For

What They Have in Common

Both Palmitoyl Tetrapeptide-7 and AHK-Cu are commonly used for:

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