Oxytocin vs Selank

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Oxytocin

Oxytocin is a natural hormone produced in the hypothalamus, often called the 'love hormone' or 'bonding hormone.' It plays key roles in social bonding, childbirth, lactation, and stress regulation.

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Selank

Selank is a synthetic peptide derived from the naturally occurring immunomodulatory peptide tuftsin. Developed in Russia for anxiety and cognitive enhancement.

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Side-by-Side Comparison

Aspect	Oxytocin	Selank
Dose Range	24 mcg–48 mcg	300 mcg–900 mcg
Frequency	1x daily	2x daily
Cycle Length	2–4 weeks	2–4 weeks
Route	intranasal	intranasal
Mechanism	Binds to oxytocin receptors in the brain and peripheral tissues. Promotes social bonding, reduces anxiety and stress response, and has various peripheral effects on smooth muscle contraction.	Modulates the expression of brain-derived neurotrophic factor (BDNF) and affects serotonin and norepinephrine systems. Has immunomodulatory and anxiolytic properties.
Typical Dosage	Intranasal: 20-40 IU (international units) for social/anxiolytic effects. Clinical uses (labor induction) require IV administration under medical supervision.	Intranasal administration: 250-500mcg 2-3 times daily. Subcutaneous: 250-500mcg daily.
Administration	Intranasal spray for behavioral effects. IV only in clinical settings. Sublingual also possible. Best used situationally rather than continuously.	Most commonly administered intranasally for cognitive effects. Can also be injected subcutaneously.
Side Effects	Intranasal: headache, nasal irritation, drowsiness. May cause over-attachment or emotional sensitivity. IV (clinical): uterine hyperstimulation, water retention.	Generally well-tolerated. Some users report mild fatigue or nasal irritation with intranasal use.
Best For	Sleep Quality Cognitive Performance	Cognitive Performance