NA-Semax Amidate vs Oxytocin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

NA-Semax Amidate

NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.

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Oxytocin

Oxytocin is a natural hormone produced in the hypothalamus, often called the 'love hormone' or 'bonding hormone.' It plays key roles in social bonding, childbirth, lactation, and stress regulation.

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Side-by-Side Comparison

AspectNA-Semax AmidateOxytocin
MechanismMaintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action.Binds to oxytocin receptors in the brain and peripheral tissues. Promotes social bonding, reduces anxiety and stress response, and has various peripheral effects on smooth muscle contraction.
Typical DosageIntranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax.Intranasal: 20-40 IU (international units) for social/anxiolytic effects. Clinical uses (labor induction) require IV administration under medical supervision.
AdministrationIntranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution.Intranasal spray for behavioral effects. IV only in clinical settings. Sublingual also possible. Best used situationally rather than continuously.
Side EffectsMay cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated.Intranasal: headache, nasal irritation, drowsiness. May cause over-attachment or emotional sensitivity. IV (clinical): uterine hyperstimulation, water retention.
Best For

What They Have in Common

Both NA-Semax Amidate and Oxytocin are commonly used for:

Key Differences

Unique to Oxytocin:

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