NA-Semax Amidate vs Liraglutide

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

NA-Semax Amidate

NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.

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Liraglutide

Liraglutide is a GLP-1 receptor agonist FDA-approved as Victoza for type 2 diabetes and Saxenda for chronic weight management. It was one of the first daily GLP-1 agonists and paved the way for newer weekly options like semaglutide.

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Side-by-Side Comparison

AspectNA-Semax AmidateLiraglutide
MechanismMaintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action.Binds to and activates GLP-1 receptors, stimulating insulin secretion in a glucose-dependent manner, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system effects.
Typical DosageIntranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax.Saxenda (weight loss): Start 0.6mg daily, increase weekly by 0.6mg to maintenance dose of 3mg daily. Victoza (diabetes): 0.6mg to 1.8mg daily.
AdministrationIntranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution.Subcutaneous injection once daily at any time, independent of meals. Rotate injection sites. Can be used with oral diabetes medications.
Side EffectsMay cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated.Nausea, vomiting, diarrhea, constipation, headache, decreased appetite. GI effects typically diminish over time with continued use.
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Key Differences

Unique to NA-Semax Amidate:

Unique to Liraglutide:

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