GHRP-2 vs SHLP2

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

GHRP-2

Growth Hormone Releasing Peptide 2 (GHRP-2) is considered one of the most potent GHRPs available. It provides strong GH release with moderate hunger increase compared to GHRP-6.

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SHLP2

SHLP2 (Small Humanin-Like Peptide 2) is a mitochondrial-derived peptide similar to humanin. It has shown insulin-sensitizing and cytoprotective effects in research, with potential metabolic benefits.

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Side-by-Side Comparison

AspectGHRP-2SHLP2
MechanismBinds to the ghrelin receptor (GHS-R) to stimulate GH release from the pituitary. Also has some direct effects on the hypothalamus. Causes less appetite increase than GHRP-6.Enhances insulin sensitivity and glucose uptake. Provides cytoprotective effects similar to humanin. May act through similar but distinct receptor pathways.
Typical DosageTypical dosing: 100-300mcg administered 2-3 times daily. Often stacked with GHRH peptides for enhanced GH release.Research compound with doses in the microgram to low milligram range studied in animal models. Human dosing not established.
AdministrationSubcutaneous injection on an empty stomach. Can be used at bedtime to enhance natural GH pulse during sleep.Subcutaneous or intraperitoneal injection in research settings. Various SHLP analogs (1-6) have different properties.
Side EffectsModerate hunger increase, water retention, potential prolactin and cortisol elevation (less than GHRP-6), tingling sensations.Limited data. Animal studies suggest good tolerability. May affect glucose metabolism.
Best For

What They Have in Common

Both GHRP-2 and SHLP2 are commonly used for:

Key Differences

Unique to GHRP-2:

Unique to SHLP2:

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