Epithalamin vs NA-Semax Amidate

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Epithalamin

Epithalamin is a natural peptide extract from the pineal gland. It is the precursor compound from which the synthetic Epitalon was derived. Known for anti-aging and telomerase-activating properties.

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NA-Semax Amidate

NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.

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Side-by-Side Comparison

AspectEpithalaminNA-Semax Amidate
MechanismSimilar to Epitalon, it stimulates telomerase production and may help maintain telomere length. Also regulates melatonin synthesis and circadian rhythms.Maintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action.
Typical DosageResearch dosing: 10-20mg daily for 10-20 day cycles. Often administered 1-3 times per year in long-term protocols.Intranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax.
AdministrationIntramuscular or subcutaneous injection. Natural extract may have more variable composition than synthetic Epitalon.Intranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution.
Side EffectsGenerally well-tolerated. May affect sleep patterns. Less characterized than synthetic Epitalon.May cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated.
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Key Differences

Unique to Epithalamin:

Unique to NA-Semax Amidate:

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