Epithalamin vs HGH Fragment 176-191

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Epithalamin

Epithalamin is a natural peptide extract from the pineal gland. It is the precursor compound from which the synthetic Epitalon was derived. Known for anti-aging and telomerase-activating properties.

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HGH Fragment 176-191

HGH Fragment 176-191 is the fat-reducing portion of the growth hormone molecule. Unlike AOD-9604 (which has an additional tyrosine), this is the exact fragment of HGH responsible for lipolytic effects.

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Side-by-Side Comparison

AspectEpithalaminHGH Fragment 176-191
MechanismSimilar to Epitalon, it stimulates telomerase production and may help maintain telomere length. Also regulates melatonin synthesis and circadian rhythms.Mimics the lipolytic region of growth hormone, stimulating fat breakdown and inhibiting lipogenesis without affecting blood sugar or promoting growth. Works independently of GH receptors.
Typical DosageResearch dosing: 10-20mg daily for 10-20 day cycles. Often administered 1-3 times per year in long-term protocols.Typical dosing: 250-500mcg daily, often split into 2-3 doses. Usually administered on empty stomach, often with fasted cardio.
AdministrationIntramuscular or subcutaneous injection. Natural extract may have more variable composition than synthetic Epitalon.Subcutaneous injection. Best results when used fasted and combined with exercise. Avoid eating for 30 minutes post-injection.
Side EffectsGenerally well-tolerated. May affect sleep patterns. Less characterized than synthetic Epitalon.Generally well-tolerated. May cause injection site irritation, temporary lethargy, or headache. Does not affect blood glucose significantly.
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Key Differences

Unique to Epithalamin:

Unique to HGH Fragment 176-191:

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