Epithalamin vs Cortexin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Epithalamin

Epithalamin is a natural peptide extract from the pineal gland. It is the precursor compound from which the synthetic Epitalon was derived. Known for anti-aging and telomerase-activating properties.

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Cortexin

Cortexin is a polypeptide complex derived from pig brain cortex, used clinically in Russia and Eastern Europe for neurological conditions including stroke recovery, traumatic brain injury, and cognitive decline.

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Side-by-Side Comparison

AspectEpithalaminCortexin
MechanismSimilar to Epitalon, it stimulates telomerase production and may help maintain telomere length. Also regulates melatonin synthesis and circadian rhythms.Contains a mixture of neuropeptides and amino acids that support neuronal metabolism, provide neuroprotection, and enhance synaptic transmission. Specific mechanisms not fully characterized.
Typical DosageResearch dosing: 10-20mg daily for 10-20 day cycles. Often administered 1-3 times per year in long-term protocols.Clinical protocols: 10mg intramuscularly once daily for 10-20 days. May be repeated after 3-6 month interval.
AdministrationIntramuscular or subcutaneous injection. Natural extract may have more variable composition than synthetic Epitalon.Intramuscular injection. Comes as lyophilized powder requiring reconstitution. Treatment given in courses rather than continuously.
Side EffectsGenerally well-tolerated. May affect sleep patterns. Less characterized than synthetic Epitalon.Generally well-tolerated. May cause injection site reactions or mild allergic responses in sensitive individuals.
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Key Differences

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