Epitalon vs Palmitoyl Tetrapeptide-7

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Epitalon

Epitalon (Epithalon) is a synthetic tetrapeptide based on the natural peptide epithalamin, produced by the pineal gland. It is primarily studied for its effects on telomerase activation.

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Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 is an anti-inflammatory peptide that reduces IL-6 secretion. Combined with Palmitoyl Tripeptide-1, it forms Matrixyl 3000, addressing both collagen production and inflammation.

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Side-by-Side Comparison

AspectEpitalonPalmitoyl Tetrapeptide-7
MechanismStimulates telomerase production, which can lengthen telomeres on DNA strands. May also regulate melatonin production and circadian rhythms.Suppresses interleukin-6 (IL-6) production, reducing inflammation that contributes to skin aging. The anti-inflammatory effect complements collagen-stimulating peptides.
Typical DosageTypical protocols: 5-10mg daily for 10-20 days, repeated 2-3 times per year.Topical: Usually combined with Palmitoyl Tripeptide-1 at similar concentrations (2-4%) in the Matrixyl 3000 complex.
AdministrationSubcutaneous or intramuscular injection. Usually administered in cycles rather than continuously.Topical application with other anti-aging actives. The palmitoyl group enhances delivery into the skin.
Side EffectsGenerally well-tolerated. May affect sleep patterns initially.Excellent tolerability profile. Anti-inflammatory properties may actually soothe sensitive skin.
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Key Differences

Unique to Epitalon:

Unique to Palmitoyl Tetrapeptide-7:

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