Dulaglutide vs Adamax

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Dulaglutide

Dulaglutide (Trulicity) is a once-weekly GLP-1 receptor agonist for type 2 diabetes. Its larger molecular size from fusion with an Fc fragment extends half-life and may reduce some GI side effects.

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Adamax

Adamax is a modified version of Semax with an adamantane group attached, designed to enhance its nootropic effects and extend duration of action compared to standard Semax.

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Side-by-Side Comparison

AspectDulaglutideAdamax
MechanismGLP-1 analog fused to a modified human IgG4 Fc fragment, providing extended duration of action. Activates GLP-1 receptors for glucose-dependent insulin secretion and appetite suppression.Similar to Semax - enhances BDNF expression and modulates dopamine/serotonin systems. The adamantane modification may increase lipophilicity and CNS penetration.
Typical DosageStart at 0.75mg once weekly, may increase to 1.5mg, 3mg, or maximum 4.5mg weekly based on glycemic response.Intranasal: 100-500mcg 1-2 times daily. Lower doses than standard Semax may be effective due to enhanced potency.
AdministrationSubcutaneous injection once weekly, any time of day, with or without food. Comes in pre-filled single-dose pens.Intranasal spray is most common route. More stable than standard Semax. Often used for acute cognitive enhancement.
Side EffectsNausea, diarrhea, vomiting, abdominal pain, decreased appetite. Generally well-tolerated with gradual dose titration.Similar to Semax - possible irritability, hair shedding, or overstimulation. May have stronger effects than standard Semax.
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Key Differences

Unique to Dulaglutide:

Unique to Adamax:

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