DSIP vs SHLP2

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

DSIP

Delta Sleep-Inducing Peptide is a neuropeptide that promotes delta wave sleep, the deepest and most restorative phase of the sleep cycle.

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SHLP2

SHLP2 (Small Humanin-Like Peptide 2) is a mitochondrial-derived peptide similar to humanin. It has shown insulin-sensitizing and cytoprotective effects in research, with potential metabolic benefits.

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Side-by-Side Comparison

AspectDSIPSHLP2
MechanismModulates sleep-wake cycles by affecting sleep spindles and delta rhythms. May also influence stress hormones and have analgesic properties.Enhances insulin sensitivity and glucose uptake. Provides cytoprotective effects similar to humanin. May act through similar but distinct receptor pathways.
Typical DosageTypical dosing: 100-300mcg administered 30 minutes before sleep. Some protocols use it cyclically.Research compound with doses in the microgram to low milligram range studied in animal models. Human dosing not established.
AdministrationSubcutaneous or intramuscular injection before bedtime. Some users report better results with cyclical use.Subcutaneous or intraperitoneal injection in research settings. Various SHLP analogs (1-6) have different properties.
Side EffectsMay cause grogginess upon waking, vivid dreams, or temporary headaches.Limited data. Animal studies suggest good tolerability. May affect glucose metabolism.
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Key Differences

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