DSIP vs Palmitoyl Tetrapeptide-7

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

DSIP

Delta Sleep-Inducing Peptide is a neuropeptide that promotes delta wave sleep, the deepest and most restorative phase of the sleep cycle.

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Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 is an anti-inflammatory peptide that reduces IL-6 secretion. Combined with Palmitoyl Tripeptide-1, it forms Matrixyl 3000, addressing both collagen production and inflammation.

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Side-by-Side Comparison

AspectDSIPPalmitoyl Tetrapeptide-7
MechanismModulates sleep-wake cycles by affecting sleep spindles and delta rhythms. May also influence stress hormones and have analgesic properties.Suppresses interleukin-6 (IL-6) production, reducing inflammation that contributes to skin aging. The anti-inflammatory effect complements collagen-stimulating peptides.
Typical DosageTypical dosing: 100-300mcg administered 30 minutes before sleep. Some protocols use it cyclically.Topical: Usually combined with Palmitoyl Tripeptide-1 at similar concentrations (2-4%) in the Matrixyl 3000 complex.
AdministrationSubcutaneous or intramuscular injection before bedtime. Some users report better results with cyclical use.Topical application with other anti-aging actives. The palmitoyl group enhances delivery into the skin.
Side EffectsMay cause grogginess upon waking, vivid dreams, or temporary headaches.Excellent tolerability profile. Anti-inflammatory properties may actually soothe sensitive skin.
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Key Differences

Unique to DSIP:

Unique to Palmitoyl Tetrapeptide-7:

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