DSIP vs Follistatin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

DSIP

Delta Sleep-Inducing Peptide is a neuropeptide that promotes delta wave sleep, the deepest and most restorative phase of the sleep cycle.

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Follistatin

Follistatin is a glycoprotein that inhibits myostatin, the protein responsible for limiting muscle growth. By blocking myostatin, follistatin can theoretically allow for increased muscle development beyond natural limits.

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Side-by-Side Comparison

AspectDSIPFollistatin
MechanismModulates sleep-wake cycles by affecting sleep spindles and delta rhythms. May also influence stress hormones and have analgesic properties.Binds to and neutralizes myostatin and activin, both of which are negative regulators of muscle mass. This removes the natural brake on muscle growth, allowing for enhanced hypertrophy.
Typical DosageTypical dosing: 100-300mcg administered 30 minutes before sleep. Some protocols use it cyclically.Research protocols typically use 100-300mcg daily, though optimal dosing is not well established. Gene therapy approaches have also been studied.
AdministrationSubcutaneous or intramuscular injection before bedtime. Some users report better results with cyclical use.Subcutaneous injection. Different isoforms exist (FS344, FS315) with varying properties. Requires careful sourcing due to complexity.
Side EffectsMay cause grogginess upon waking, vivid dreams, or temporary headaches.Limited human data. Theoretical concerns about effects on other organs where activin signaling is important.
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Key Differences

Unique to DSIP:

Unique to Follistatin:

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