CJC-1295 vs NA-Semax Amidate

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

CJC-1295

CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to produce more growth hormone.

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NA-Semax Amidate

NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.

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Side-by-Side Comparison

AspectCJC-1295NA-Semax Amidate
MechanismCJC-1295 binds to GHRH receptors in the pituitary, triggering increased production and release of growth hormone. The DAC (Drug Affinity Complex) version extends half-life significantly.Maintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action.
Typical DosageCJC-1295 DAC: 1-2mg weekly. CJC-1295 no DAC (Mod GRF 1-29): 100-300mcg 2-3 times daily.Intranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax.
AdministrationSubcutaneous injection, often combined with a GHRP like Ipamorelin for synergistic effects. Best administered before sleep or fasted.Intranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution.
Side EffectsWater retention, tingling in extremities, potential increase in cortisol and prolactin levels.May cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated.
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Key Differences

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