CJC-1295 vs DSIP
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
CJC-1295
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to produce more growth hormone.
Full details →DSIP
Delta Sleep-Inducing Peptide is a neuropeptide that promotes delta wave sleep, the deepest and most restorative phase of the sleep cycle.
Full details →Side-by-Side Comparison
| Aspect | CJC-1295 | DSIP |
|---|---|---|
| Dose Range | 1 mg–2 mg | 100 mcg–300 mcg |
| Frequency | Less than daily | 1x daily |
| Cycle Length | 8–12 weeks | 1–6 weeks |
| Route | subcutaneous | subcutaneous |
| Mechanism | CJC-1295 binds to GHRH receptors in the pituitary, triggering increased production and release of growth hormone. The DAC (Drug Affinity Complex) version extends half-life significantly. | Modulates sleep-wake cycles by affecting sleep spindles and delta rhythms. May also influence stress hormones and have analgesic properties. |
| Typical Dosage | CJC-1295 DAC: 1-2mg weekly. CJC-1295 no DAC (Mod GRF 1-29): 100-300mcg 2-3 times daily. | Typical dosing: 100-300mcg administered 30 minutes before sleep. Some protocols use it cyclically. |
| Administration | Subcutaneous injection, often combined with a GHRP like Ipamorelin for synergistic effects. Best administered before sleep or fasted. | Subcutaneous or intramuscular injection before bedtime. Some users report better results with cyclical use. |
| Side Effects | Water retention, tingling in extremities, potential increase in cortisol and prolactin levels. | May cause grogginess upon waking, vivid dreams, or temporary headaches. |
| Best For |
What They Have in Common
CJC-1295, DSIP are both commonly used for:
Key Differences
Unique to CJC-1295:
Unique to DSIP:
Which Has Stronger Evidence?
- Sleep Quality: DSIP has stronger research support.
| Goal | CJC-1295 | DSIP |
|---|---|---|
| Sleep Quality | medium | high |
Key Studies
CJC-1295
- A method for confirming CJC-1295 abuse in equine plasma samples by LC-MS/MS.
Drug testing and analysis, 2019
- An immuno polymerase chain reaction screen for the detection of CJC-1295 and other growth-hormone-releasing hormone analogs in equine plasma.
Drug testing and analysis, 2019
- Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions.
Substance use & misuse, 2016
DSIP
- Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models.
Frontiers in pharmacology, 2024
- Delta sleep-inducing peptide (DSIP): a still unresolved riddle.
Journal of neurochemistry, 2006
- [DSIP: the sleep peptide or an unknown hypothalamic hormone?].
Zhurnal evoliutsionnoi biokhimii i fiziologii, 1994
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