AOD-9604 vs Cortexin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

AOD-9604

AOD-9604 is a modified fragment of human growth hormone (HGH fragment 176-191). It was developed to have the fat-reducing effects of growth hormone without the adverse effects on blood sugar or growth.

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Cortexin

Cortexin is a polypeptide complex derived from pig brain cortex, used clinically in Russia and Eastern Europe for neurological conditions including stroke recovery, traumatic brain injury, and cognitive decline.

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Side-by-Side Comparison

AspectAOD-9604Cortexin
MechanismStimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat accumulation) without affecting blood sugar or growth. Works specifically on adipose tissue through a mechanism independent of GH receptors.Contains a mixture of neuropeptides and amino acids that support neuronal metabolism, provide neuroprotection, and enhance synaptic transmission. Specific mechanisms not fully characterized.
Typical DosageResearch dosing typically ranges from 250-500mcg daily, often split into morning and afternoon doses. Some protocols use higher doses up to 1mg.Clinical protocols: 10mg intramuscularly once daily for 10-20 days. May be repeated after 3-6 month interval.
AdministrationSubcutaneous injection, typically in the abdominal area. Best administered on an empty stomach. Can be combined with exercise for enhanced effects.Intramuscular injection. Comes as lyophilized powder requiring reconstitution. Treatment given in courses rather than continuously.
Side EffectsGenerally well-tolerated. May cause headaches, injection site reactions, or temporary lethargy. Does not affect blood glucose like full GH.Generally well-tolerated. May cause injection site reactions or mild allergic responses in sensitive individuals.
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Key Differences

Unique to AOD-9604:

Unique to Cortexin:

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