Cetrorelix

FDA approved

Cetrorelix (Cetrotide) is a GnRH antagonist approved by the FDA in 2000 for use in IVF and other fertility treatments, to stop premature ovulation during ovarian stimulation.

At a glance

Where it acts: Sexual & reproductive
Regulatory status: FDA approvedApproved by the U.S. FDA for at least one medical use.

Mechanism of Action

Cetrorelix is a 10-amino acid peptide that blocks pituitary GnRH receptors, immediately suppressing the LH surge that would otherwise release eggs before they can be retrieved.

Typical Dosage (Research)

Prescription-only medicine. Dosing is set by a physician according to the FDA-approved label and the condition being treated.

Side Effects & Risks

Injection site reactions, headache and nausea.

Ovarian hyperstimulation syndrome as part of fertility treatment, and rare severe allergic reactions. Contraindicated in pregnancy.

Who Uses Cetrorelix

Women undergoing controlled ovarian stimulation for IVF.